Not really. Email addresses that belong to an "opt in" list have opted to receive emails from, say, the list-purchasing company -- not your company. Even if the opt-in process includes language like, "Opt in to receive information from us, or offers from other companies we think you might enjoy," the fact is the recipient doesn't recall having a prior relationship with you, specifically. This makes it highly likely for the recipients to mark you as "spam" when you arrive in their inboxes. Hey, if they don't recognize you or remember opting in to communications from you ... can you blame them?
Dynamic segmentation – As alluded to earlier, you can’t just send out a generic message to everyone on your list. While basic demographic data can be used to segment your list, that’s far from taking the dynamic approach. Automation tools can help you segment your list as they go through the funnel, allowing you to send personalized messaging depending on their actions and behaviors.